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(A) MRI of patient III-1 in family A at 53 years of age showing marked midline cerebellar atrophy, mildly enlarged lateral ventricle, and normal corpus callosum. (B) MRI of patient A IV-1 at 32 years of age showing marked midline cerebellar atrophy before the onset of ataxia but having cognitive disability and autism spectrum disorder. (C and D) MRI of patient III-2 in family B at 48 years of age showing midline (C) and lateral (D) cerebellar atrophy.
