Figure 1. GT1b is upregulated and released in the spinal cord after nerve injury.

• A
  A LC‐MRM/MS analysis of ganglioside GT1b species in pooled spinal cord tissues of Sham‐operated or nerve‐injured mice at 3 dpi. Representative traces of GT1b species (d18:1–18:0) are shown, and the intensity of the GT1b species is presented as the fold induction compared to the corresponding control. GM3‐d3 served as internal standard for normalization. d18:1–18:0 means the ceramide structure (carbon number: double bond number), and d3 means deuterated form.
• B, C
  GT1b level in ISF (B) and CSF (C) was analyzed by ELISA. Data are represented as mean ± SEM (Student's t‐test, *P < 0.05, ***P < 0.001).