Table 1.

Assessments of changes in microarchitectural properties with osteoporosis induction after OVX performed on day 90. Day 0 is the day of the tibial surgery.

	Bone volume fraction (%)	Structure model index (-)	Connectivity density (mm−3)	Trabecular thickness (μm)	Trabecular separation (μm)	Degree of anisotropy (-)	Bone surface density (mm−3)	Bone surface-to-volume ratio (mm−3)	Apparent density (mg/cm3)	Material density (mg/cm3)
Day 90	54 ± 8	-1.4 ± 1.6	1324 ± 282	63 ± 5	56 ± 9	1.4 ± 0.03	19.1 ± 1.4	34 ± 5	505 ± 52	863 ± 16
Day 7	19 ± 12	3.3 ± 0.9	248 ± 230	62 ± 3	160 ± 50	1.4 ± 0.06	7.8 ± 4.3	44 ± 4	234 ± 100	888 ± 9
Day 0	17 ± 12	3.3 ± 0.9	210 ± 198	59 ± 3	173 ± 55	1.4 ± 0.58	6.8 ± 4.6	46 ± 4	217 ± 105	884 ± 12
ANOVA	p < 0.001	p < 0.001	p < 0.001	p = 0.097	p < 0.001	p < 0.001	p < 0.001	p < 0.001	p < 0.001	p < 0.001