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. 2020 Jan 29;11(2):143. doi: 10.3390/genes11020143

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Impact of the L119F-GSTe2 mediated metabolic resistance on bednet efficacy -exophily: (A) Genotype distribution of L119F-GSTe2 between indoor (Room) and outdoor (verandah) mosquitoes after exposure to Olyset showing no association; (B) Genotype distribution of L119F-GSTe2 between indoor (Room) and outdoor (verandah) mosquitoes after exposure to Olyset Plus showing a significant increased ability to exit the room when considering all mosquitoes; (C) A greater association is observed with exophily with Olyset Plus when only analyzing unfed mosquitoes; (D) Genotype distribution of L119F-GSTe2 between indoor (Room) and outdoor (verandah) mosquitoes after exposure to PermaNet 2.0 showing a significant association (RS vs. SS: OR = 1.35; p < 0.01); (E) Genotype distribution of L119F-GSTe2 between indoor (Room) and outdoor (verandah) mosquitoes after exposure to PermaNet 3.0 showing no association.