Table 3.
Cytotoxic activities of compounds 1–13 (IC50 ± SD, μM, n = 3).
| Compounds | Human Nasopharyngeal Carcinoma Cell Lines | Human Hepatocellular Cancer Cell Lines | ||||
|---|---|---|---|---|---|---|
| CNE1 | CNE2 | HONE1 | SUNE1 | HepG2 | QGY7701 | |
| 1 | − a | − | − | 90.55 ± 1.58 | − | − |
| 2 | − | − | − | 92.53 ± 1.10 | − | − |
| 3 | 81.91 ±1.81 | − | − | − | − | − |
| 4 | 63.88 ± 1.22 | − | − | 92.78 ± 1.73 | − | − |
| 5 | − | 91.78 ± 1.90 | − | 64.35 ± 0.89 | − | − |
| 6 | − | 75.70 ± 1.09 | − | 72.07 ± 0.65 | 1.72 ± 0.35 | 0.71 ± 0.12 |
| 7 | − | 85.66 ± 1.69 | − | 28.12 ± 0.75 | 9.60 ± 0.46 | 7.12 ± 0.36 |
| 8 | − | − | − | 39.38 ± 0.58 | 46.10 ± 0.91 | 31.62 ± 1.23 |
| 9 | 70.96 ± 1.51 | − | − | − | − | − |
| 10 | 72.72 ± 1.36 | − | − | − | − | − |
| 11 | 92.87 ± 2.10 | − | − | − | − | − |
| 12 | − | − | − | − | − | − |
| 13 | 50.55 ± 0.88 | − | − | − | − | − |
| Hirsutanol A | 10.08 ± 0.92 | 12.72 ± 0.86 | 17.40 ± 0.52 | 3.50 ± 0.28 | 10.11 ± 0.69 | 21.12 ± 1.01 |
a In the table, “−” means IC50 value > 100 μΜ.