Table 1.
Clinical and histopathological characteristics of patients with bladder carcinoma (BlCa), normal bladder mucosae (NB), healthy donors (HD) and inflammatory controls (IC).
| Tissues | Urines | ||||||
|---|---|---|---|---|---|---|---|
| Testing Set | Validation Sets | ||||||
| Clinicopaphological Features | Bladder UC | Normal Bladder Mucosae | Bladder UC | Healthy Donors | Bladder UC | Healthy Donors (#1) | Inflammatory Controls (#2) |
| Patients, n | 94 | 19 | 27 | 24 | 100 | 57 | 174 |
| Gender, n | |||||||
| Males | 78 | 19 | 20 | 13 | 79 | 16 | 132 |
| Females | 16 | 0 | 7 | 12 | 21 | 41 | 42 |
| Median age, yrs (range) | 69 (45–91) |
63 (48–75) |
69 (47–88) |
45 (39–61) |
68 (38–91) |
49 (41–64) |
64 (18–92) |
| Grade, n | |||||||
| Papillary, low-grade | 34 | n.a. | 13 | n.a. | 51 | n.a. | n.a. |
| Papillary, high-grade | 33 | n.a. | 8 | n.a. | 26 | n.a. | n.a. |
| Invasive, high-grade | 27 | n.a. | 6 | n.a. | 23 | n.a. | n.a. |
| Invasion of Muscular Layer, n | |||||||
| NMIBC | 67 | n.a. | 19 | n.a. | 77 | n.a. | n.a. |
| MIBC | 27 | n.a. | 8 | n.a. | 23 | n.a. | n.a. |
#1—Validation Set #1; #2—Validation Set #2; yrs—years; n.a.—non applicable; NMIBC—Non-Muscle Invasive Bladder Cancer; MIBC—Muscle Invasive Bladder Cancer, UC—Urothelial Carcinoma.