Table 2.

The predictive factors associated with drug-resistant seizure in patients with diffuse astrocytic and oligodendroglial tumors

Characteristics	Odds ratio (95% CI)	P-value
Age	0.940 (0.884–1.000)	0.050
Sex	2.880 (0.603–13.749)	0.185
Origin (fronto-temporal lobe)	3.900 (0.351–43.364)	0.268
Existence of preoperative seizure (−/+)	0.375 (0.056-2.519)	0.313
Extent of tumor removal (<95% or ≥95%)	0.900 (0.172–4.699)	0.901
Temozolomide (−/+)	1.250 (0.251–6.235)	0.785
Radiation (−/+)	2.143 (0.436–10.526)	0.348
Tumor volume after treatment (<50% or ≥50%)	4.278 (0.798–22.928)	0.090
Recurrence (−/+)	2.917 (0.594–14.327)	0.187
Neurological symptoms (−/+)	11.143 (1.108–112.012)	0.041
Karnofsky Performance Scale	0.974 (0.939–1.010)	0.161
IDH-1 (−/+)	0.267 (0.041–1.727)	0.165
1p/19q co-deletion (−/+)	0.136 (0.022–0.860)	0.034
Olig2 (−/+)	0.225 (0.042–1.194)	0.080
PDGFR-α (−/+)	0.875 (0.191–3.999)	0.863
p53 (−/+)	21.600 (2.135–218.579)	0.009
ATRX (−/+)	0.833 (0.179–3.884)	0.816
Ki67 (<5/≥5)	1.143 (0.250–5.224)	0.863

P <0.05 was considered to be indicative of statistical significance.