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Diabetes-induced oxidative stress is decreased in mice with conditional inactivation of endothelial ADAM17. (A) Representative images of DHE-stained retinal sections from control normoglycemic and diabetic ADAM17flox and ADAM17Cre-flox mice. n = 3. Scale bar: 50 µm. (B) Dot blot analysis of 4-HNE and 3-NT in retinal tissue from control normoglycemic and diabetic ADAM17flox and ADAM17Cre-flox mice. Cont, control; Diab, diabetic. n = 3.
