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Effect of high glucose on ADAM17 expression in vitro. (A) QPCR analysis of ADAM17 mRNA. (B) Representative blots and densitometry analysis of ADAM17 protein expression in HREC treated with 5 mM D-glucose (NG, normal glucose) or 25 mM D-glucose (HG, high glucose) for 24–48 h. L-glucose (LG, 25 mM) served as the osmotic control). * p < 0.001 NG vs. HG. Data presented as mean ± SE. n = 3.
