Reagent/resource	Reference or source	Identifier or catalog number
Experimental models
HeLa cell lines panel	Liu et al (2019), NBT, Appendix Table S1
Cell culture and pulse SILAC labelling
Dulbecco's modified Eagle medium	Gibco	41965‐039
SILAC Dulbecco's modified Eagle medium High Glucose medium	GE Healthcare
Dialyzed FBS	PAN Biotech	P30‐2101
Penicillin/streptomycin	Gibco	15140122
l‐lysine (13C6 15N2)	Chemie Brunschwig AG
l‐arginine (13C6 15N4)	Chemie Brunschwig AG
l‐lysine	Sigma Aldrich	L5501
l‐arginine	Sigma Aldrich	A5006
l‐proline	Sigma Aldrich	81709
Chemicals, enzymes and other reagents
Tris‐(2‐carboxyethyl)‐phosphine	Sigma Aldrich	C4706
Iodoacetamide	Sigma Aldrich	I1149
Ammonium bicarbonate	Sigma Aldrich	9830
Sequencing‐grade porcine trypsin	Promega	V5113
Software
Spectronaut™ Professional+	Biognosys AG	v13
Perseus	Tyanova et al (2016)	v1.6.2.2
R	R Core Team (2018)	v3.2.5
GraphPad Prism	GraphPad Software, Inc.	v5.04
Other
Orbitrap Fusion Lumos Tribrid mass spectrometer	Thermo Scientific
EASY‐nLC 1200 systems	Thermo Scientific