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. 2020 Feb 11;56(2):70. doi: 10.3390/medicina56020070

Table 3.

Serum level of malondialdehyde, activity of glutathione S-transferase and level of total glutathione in breast cancer patients and control group in regards to age.

Under 50 Years of Age
Parameters n Before Surgery Two Hours after Surgery Five Days after Surgery n Control
MDA,
nmol/mL
34 10.04 ± 5.2 11.68 ± 8.39 * 8.94 ± 4.24 * 20 6.06 ± 1.72
GST,
µmol/mL/min
34 0.33 ± 0.16 0.34 ± 0.17 0.33 ± 0.16 20 0.41 ± 0.19
GSH + GSSG,
µmol/mL
34 0.51 ± 0.21 0.46 ± 0.14 0.49 ± 0.24 20 0.98 ± 0.13
Over 50 Years of Age
Parameters n Before Surgery Two Hours after Surgery Five Days after Surgery n Control
MDA,
nmol/mL
18 13.67 ± 6.76 * 18.18 ± 10.76 * 11.46 ± 6.30 22 7.40 ± 1.83
GST,
µmol/mL/min
18 0.43 ± 0.13 0.44 ± 0.14 0.39 ± 0.17 22 0.55 ± 0.16
GSH + GSSG,
µmol/mL
18 0.41 ± 0.13 0.41 ± 0.11 0.47 ± 0.15 22 0.60 ± 0.17

GSH + GSSG = total glutathione; GST = glutathione S-transferase; MDA = malondialdehyde; n = number of patients.* p <0.017; p <0.05.