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. 2019 May 6;11(3):266–271. doi: 10.1021/acsmedchemlett.9b00065

Figure 5.

Figure 5

X-ray crystal structure of 9 in murine RIPK3 (magenta, PDB code 6OKO) overlaid with 9 in human c-Met kinase (green, PDB code 3CE3). Crystal structures of compound 9 are bound to the kinase catalytic domains. Oxygens are colored red, nitrogens blue, and fluorines light blue. Hydrogen bonds are indicated with dashed lines.