Scheme 2. General Synthesis of Noncommercially Available Thiols.
Reagents and conditions: (a) 2-ethylhexyl 3-mercaptopropanoate, Pd2dba3, XantPhos, DIPEA, PhMe, 110 °C; (b) NaOEt, PhMe, EtOH, rt; then acid; (c) KOtBu, THF, rt; then acid.
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