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. 2019 Aug 20;63(5):2308–2324. doi: 10.1021/acs.jmedchem.9b01112

Table 5. Effects of 2,4- vs 2,5-Substitution of Thiazole Core on LOXL2 Potency.

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a

Reported IC50 values were determined using 1 h preincubation in at least two separate experiments (n ≥ 2). When n = 2, individual IC50 values are shown. When n > 2, the values are reported as the geometric mean with the corresponding 95% confidence interval in square brackets.