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. 2020 Jan 22;9(2):317. doi: 10.3390/jcm9020317

Figure 8.

Figure 8

Inhibition of arginase limited inflammasome activation in bovine retinal endothelial cells (BRECs) treated with palmitate and high glucose (PA+HG). Representative western blots (A) of BRECs treated for 72 h with 100 µM palmitate and 25 mM of glucose (PA+HG) in the presence or absence of 2(S)-amino-6-boronohexanoic acid (ABH) showing the expression of A2 (B) and components of the inflammasome: nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain-containing protein 3 (NLRP3) (C), caspase 1 (D) and pro-interleukin-1 β (pro-IL-1β) (E,F) (n = 4–6 per group). Data are presented as mean ± SEM (standard error of the mean). * p < 0.05 compared to control (bovine serum albumin (BSA)-treated) group, # p < 0.05 compared to PA+HG treated group.