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. 2020 Feb 19;9(2):565. doi: 10.3390/jcm9020565

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Current therapeutic recommendations for clear cell renal cell cancer; IMDC, International Metastatic Renal Cell Carcinoma Database Consortium. Zero of 6 risk factors (see text): favorable risk, 1–2 of 6 risk factors: intermediate risk, ≥3 of 6 risk factors: poor risk. (1) Anti-PD-1 antibody, (2) VEGFR-TKI, (3) anti-PD-L1 antibody, (4) anti-VEGF antibody, (5) anti-CTLA-4 antibody.