Table 3.
Allele frequencies of the ARNTL, CLOCK, and PER2 polymorphisms (N = 1057).
Gene | SNP | Minor Allele | MAF MI | MAF no-MI | p-Value | q-Value |
---|---|---|---|---|---|---|
ARNTL | rs3789327 * | G | 0.425 | 0.518 | 2.27 × 10−5 | 6.05 × 10−5 |
rs4757144 | G | 0.420 | 0.442 | 0.324 | 0.432 | |
rs12363415 * | A | 0.413 | 0.338 | 4.37 × 10−4 | 8.74 × 10−4 | |
CLOCK | rs11932595 | G | 0.428 | 0.437 | 0.685 | 0.782 |
rs6811520 * | C | 0.444 | 0.620 | 7.11 × 10−15 | 5.68 × 10−14 | |
rs13124436 * | A | 0.200 | 0.301 | 1.72 × 10−7 | 6.88 × 10−7 | |
PER2 | rs35333999 | T | 0.038 | 0.055 | 0.077 | 0.123 |
rs934945 | T | 0.172 | 0.174 | 0.885 | 0.885 |
MAF, minor allele frequency; q-value, corrected significant p-value by the Benjamini–Hochberg method. * Deviation from the Hardy–Weinberg equilibrium in the MI group.