Table 2.

Associations of urinary 2Py/N¹-MN with kidney function in RTR and kidney donors before and after kidney donation ¹.

Variable	RTR	Kidney Donors
		Total Cohort	Pre-Donation	Post-Donation
	n = 660	n = 275	n = 85	n = 85
eGFR, mL/min/1.73 m2
Standardized β	−0.40	−0.17	−0.01	−0.11
p-value	<0.001	0.03	0.94	0.42
GFR, mL/min/1.73 m2
Standardized β	−0.39	−0.20	−0.02	0.15
p-value	<0.001	0.003	0.89	0.27

¹ Linear regression analyses were performed to investigate associations of urinary 2Py/N¹-MN with kidney function, with adjustment for age and sex. eGFR, estimated glomerular filtration rate; GFR, glomerular filtration rate; N¹-MN, N¹-methylnicotinamide; RTR, renal transplant recipients; 2Py, N¹-methyl-2-pyridone-5-carboxamide; 2Py/N¹-MN, ratio of 2Py to N¹-MN.