MPS
|
Mucopolysaccharidosis
|
LSD |
lysosomal storage disorder |
CNS |
central nervous system |
GAG |
glycosaminoglycan |
NAGLU |
N-acetyl-α-D-glucosaminidase |
SGSH |
N-sulfoglucosamine sulfohydrolase |
HGSNAT |
acetyl-CoA:alpha-glucosaminide N-acetyltransferase |
GNS |
N-acetylglucosamine-6-sulfate sulfatase |
IDUA |
α-L-iduronidase |
IDS |
Iduronate-2-sulfatase |
GALNS |
Galactosamine-6-sulfatase |
GLB1 |
β-galactosidase |
ARSB |
Arylsulfatase B |
CT-scan |
computed tomography scan |
MRI |
magnetic resonance imaging |
RP |
rapid progressing |
SP |
slow progressing |
OF |
open field |
ROS |
reactive oxygen species |
SOD |
superoxide dismutase |
SCMAS |
subunit C of the mitochondrial ATP synthase |
FGF |
fibroblast growth factor |
iPSC |
induced pluripotent stem cell |