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Paracrine activity of mesenchymal stromal cells (MSCs). MSC-secreted factors can interact directly at different cellular processes, such as immunomodulation, chemoattraction, progenitor cell proliferation, angiogenesis and differentiation, remaining all of them essential to the correct function of MSCs within the body. HGF: hepatocyte growth factor; IGF: insulin-like growth factor 1; TSG6: tumor necrosis factor-inducible gene 6 protein; VEGF: vascular endothelial growth factor.
