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. 2020 Mar 3;19(4):3239–3248. doi: 10.3892/ol.2020.11440

Figure 4.

Figure 4.

Inhibitory effect of miR-320 on BC cell proliferation, migration and invasion is reversed by ELF3. (A) miR-320 expression was higher in MCF-7 and SK-BR-3 cells after transfection with miR-320 mimic, and ELF3 expression was increased after transfection with ELF3 vector. (B) MCF-7 and (C) SK-BR-3 cell viability was decreased after transfection with miR-320 mimic, while it was increased when combined with ELF3 vector. (D) Cell migration and (E) invasion rates were decreased in MCF-7 and SK-BR-3 cells after transfection with miR-320 mimic, whereas they were increased after transfection with miR-320 mimic + ELF3 vector. Scale bars, 100 µm. **P<0.01. BC, breast cancer; miR, microRNA; ELF3, E74-like factor 3; OD, optical density.