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. 2020 Feb 17;9(2):539. doi: 10.3390/jcm9020539

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Proposal of a diagnostic algorithm for IPDs. According to peculiar clinical pictures (e.g., syndromic forms of IPD), or the evaluation of platelet number and size, the specific markers to be evaluated stepwise using light- and immunofluorescence microscopy are reported. Although the present diagnostic algorithm is primarily based on the evaluation of the blood smear, the use of further diagnostic tools such as platelet function tests and genetic screening should also be taken into account.