Table 3.

The anti-proliferative effects of scalaranes 1–7.

Compound	Cell lines IC50 (μM)
	MOLT-4	K-562	U-937	SUP-T1
1	39.54	NA	NA	33.02
2	34.93	NA	NA	NA
3	6.31	11.69	5.74	9.00
4	29.83	NA	NA	NA
5	0.31	3.04	2.35	5.90
6	5.67	9.71	6.97	12.33
7	1.49	1.04	5.88	7.49
Doxorubicin a	0.02	0.13	0.04	0.09

^a Doxorubicin was used as a positive control; NA: not active at 20 μg/mL for 72 h.