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. 2020 Mar 13;10(1):2045894020912937. doi: 10.1177/2045894020912937

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© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 3. — Aged mice demonstrate increased lung stiffness in the absence of hypertension. flexiVent analsysis with hemodynamics (Hdx) measurement in WT or BOE mice one year following induction. (a) Body weight, (b) hematocrit (HCT)m and (c) RV/LV+S. flexiVent analysis of (d) total resistance (Rrs), (e) system compliance (Crs), (f) elastance (Ers), (g) airway resistance (Rn), and (h) static lung compliance (Cst). (i) A pressure transducer was placed in the right ventricle to measure RVSP or the (j) left ventricle to measure LVSP followed by reinsertion into the RV to measure (k) Cardiac output (CO), (l) heart rate, and (m) systemic pressure. Data presented as mean (±SEM). The mean is indicated by +. n = 5–10 mice/group.