Table 3.
Adverse events.
Fast Metabolizers (n = 17) | Slow Metabolizers (n = 17) | p-Value | |
---|---|---|---|
DGF | 4 (24%) | 5 (29%) | 1 a |
Antibodies and rejection | |||
Preformed Class II DSA | 1 (6%) | 1 (6%) | 1 a |
Class II DSA before conversion | 1 (6%) | 1 (6%) | 1 a |
Class I DSA after conversion | 1 (6%) | 0 | 1 a |
BPAR before conversion to EVR | |||
AMR | 1 (6%) | 1 (6%) | 0.490 b |
TCMR | 1 (6%) | 2 (12%) | |
Combined AMR + TCMR | 7 (41%) | 3 (18%) | |
BPAR after conversion to EVR | |||
AMR | 0 | 0 | 0.485 a |
TCMR | 2 (12%) | 0 | |
Combined AMR + TCMR | 0 | 1 (6%) | |
Infections | |||
CMV infection before conversion | 2 (12%) | 4 (24%) | 0.656 a |
CMV infection after conversion | 1 (6%) | 0 | 1 a |
BKV infection before conversion | 2 (12%) | 1 (6%) | 1 a |
BKV infection after conversion | 0 | 0 | - |
Death | 0 | 1 (6%) | 1 a |
DGF, delayed graft function; DSA, donor-specific antibody; BPAR, biopsy-proven acute rejection; AMR, antibody-mediated rejection; TCMR, T-cell mediated rejection; EVR, everolimus. Statistics: Adverse events are reported as absolute and relative frequencies. a Fisher’s exact test.