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. 2020 Jan 23;9(2):328. doi: 10.3390/jcm9020328

Table 3.

Adverse events.

Fast Metabolizers (n = 17) Slow Metabolizers (n = 17) p-Value
DGF 4 (24%) 5 (29%) 1 a
Antibodies and rejection
Preformed Class II DSA 1 (6%) 1 (6%) 1 a
Class II DSA before conversion 1 (6%) 1 (6%) 1 a
Class I DSA after conversion 1 (6%) 0 1 a
BPAR before conversion to EVR
AMR 1 (6%) 1 (6%) 0.490 b
TCMR 1 (6%) 2 (12%)
Combined AMR + TCMR 7 (41%) 3 (18%)
BPAR after conversion to EVR
AMR 0 0 0.485 a
TCMR 2 (12%) 0
Combined AMR + TCMR 0 1 (6%)
Infections
CMV infection before conversion 2 (12%) 4 (24%) 0.656 a
CMV infection after conversion 1 (6%) 0 1 a
BKV infection before conversion 2 (12%) 1 (6%) 1 a
BKV infection after conversion 0 0 -
Death 0 1 (6%) 1 a

DGF, delayed graft function; DSA, donor-specific antibody; BPAR, biopsy-proven acute rejection; AMR, antibody-mediated rejection; TCMR, T-cell mediated rejection; EVR, everolimus. Statistics: Adverse events are reported as absolute and relative frequencies. a Fisher’s exact test.