Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 17;11(2):203. doi: 10.3390/genes11020203

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Vesicle production and secretion by murine embryos at different developmental stages shown by TEM. (A) Mouse oocyte (left) with magnifications of the production of multivesicular bodies (MVBs) in the cellular cytoplasm (center) and secretion of their content towards the zona pellucida (right). (B) E2.5 embryo (left) with magnifications of the cytoplasm containing MVBs (center) and the secretion of extracellular vesicles (EVs) through the zona pellucida (right). (C) E3.5 mouse embryo (left) showing MVB secreted to the intercellular space. (D) E4.5 blastocyst (left) secreting EVs into the zona pellucida (center) and blastocoel cavity (right). Abbreviations: B, blastomere; bl, blastocoel; O, oocyte; TE, trophectoderm cell; zp, zona pellucida.