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. 2020 Feb 13;8(2):253. doi: 10.3390/microorganisms8020253

Figure 1.

Figure 1

Sensitivity and tolerance to human serum. JSG698 was used for wild-type (WT) S. Typhi. (A) Growth from input of WT planktonic Salmonella following challenge with 30% normal human serum or heat-inactivated serum determined by colony forming unit (CFU) enumeration (data are normalized to heat-inactivated control) (n = 5). Significance between conditions was identified by multiple t tests using the Holm–Sidak method (α = 0.05) to correct for multiple comparisons (****, p < 0.000001). (B) CFU enumeration of biofilms following the same conditions as planktonic bacteria. Significance difference were tested for using two-way analysis of variance (ANOVA) and the Sidak method to correct for multiple comparisons (n = 4, daily experiments conducted in quintuplicate). Error bars indicate standard deviation (SD).