Fascin2 Expression is Decreased During Acute Injury. A. A loss of fascin2 protein expression was seen in C2, but not NT3, cells following challenge with 150 μM cisplatin for 12–24 h. B. Densitometric analysis of three replicate experiments; protein expression is shown as the fold decrease from control (C2, 0 h). Each data point represents the mean + SE of three samples, * indicates a significant difference from control. C. Fascin2 expression is decreased in aged (24 mon), but not young (4 mon) kidney 72 h (peak of injury) after cisplatin challenge (2.75 mg/kg). Each lane is a sample from an individual rat. D. Densitometric analysis of four replicate experiments; protein expression is shown as the fold decrease from control (4 mon control). Each data point represents the mean + SE of four samples, * indicates a significant difference from control.