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Fascin2 Rescues Mitochondrial Dysfunction in Cisplatin-Induced Nephrotoxicity. A. Fascin2 attenuates loss of ATP following cisplatin challenge. B. Oxygen consumption of complex I and II in C2 cells is corrected by fascin2 overexpression. C. Cisplatin induces increased oxidative stress in C2 cells; an effect attenuated by fascin2. Data points represent the mean ± SE of 12 replicates; *indicates a significant difference from control (NT3/V).
