Table 3.
Compositional change values of the fecal microbiota at the genus level.
| Genus | Compositional Change (%) | p Value | q Value | |
|---|---|---|---|---|
| CP1563-10-HOA | Placebo | |||
| Blautia | −2.1 ± 1.2 | −0.8 ± 1.0 | 0.39 | 0.45 |
| Bifidobacterium | −0.0 ± 1.2 | 1.3 ± 1.3 | 0.44 | 0.45 |
| Faecalibacterium | 0.8 ± 1.1 | 2.0 ± 1.1 | 0.45 | 0.45 |
| Coprococcus | −1.1 ± 0.6 | −1.3 ± 0.7 | 0.80 | 0.57 |
| Lachnospiraceae;g_[Ruminococcus] | −0.7 ± 0.5 | −1.3 ± 0.6 | 0.43 | 0.45 |
| Lachnospiraceae;g | 1.0 ± 0.4 | −0.6 ± 0.5 | 0.01 | 0.047 |
| Roseburia | 0.8 ± 0.7 | −1.4 ± 0.6 | 0.01 | 0.047 |
| Bacteroides | 1.5 ± 1.3 | 2.3 ± 1.0 | 0.64 | 0.53 |
| Streptococcus | −0.8 ± 0.5 | 0.2 ± 0.6 | 0.21 | 0.37 |
| Ruminococcus | 0.4 ± 0.4 | −0.3 ± 0.3 | 0.22 | 0.37 |
| Dorea | −0.1 ± 0.2 | −0.2 ± 0.2 | 0.88 | 0.59 |
| Erysipelotrichaceae;g_[Eubacterium] | −0.0 ± 0.2 | −0.1 ± 0.2 | 0.80 | 0.57 |
| Lachnospiraceae;Other | 0.1 ± 0.1 | 0.0 ± 0.1 | 0.62 | 0.53 |
| Butyricicoccus | 0.0 ± 1.1 | −0.4 ± 0.1 | 0.046 | 0.12 |
| Collinsella | −0.3 ± 0.1 | 0.2 ± 0.1 | 0.003 | 0.03 |
Values are the mean ± SEM (the CP1563-10-HOA group: n = 80, the placebo group: n = 83). The p values were calculated by Student’s t-test and adjusted using the false discovery rate (FDR) method. FDR-adjusted p values (q values) are listed.