Table 1.
Nano-size distribution of silica nanoparticles in water and culture media by DLS. LS30 for Ludox® LS silica from Grace, SiG for Sicastar®-greenF, RPMI for Roswell Park Memorial Institute 1640 medium, FBS for fetal bovine serum. The Z-average of particles and their proportion in the solution are reported.
| Nanoparticle | Solvant | Peak 1 | Peak 2 | Peak 3 |
|---|---|---|---|---|
| SiG (40 µg/mL) |
H2O | 33.8 nm (100%) | 0 | 0 |
| RPMI | 34.4 nm (100%) | 0 | 0 | |
| RPMI 10% FBS | 7.99 nm (22.8%) | 43.5 m (74.4%) | 527 nm (2.9%) | |
| LS30 (20 µg/mL) |
H2O | 24 nm (100%) | 0 | 0 |
| RPMI | 22.6 nm (100%) | 0 | 0 | |
| RPMI 10% FBS | 10.3 nm (17.7%) | 63.3 nm (82.3%) | 0 | |
| Media | H2O | 0 | 0 | 0 |
| RPMI | 0 | 0 | 0 | |
| RPMI 10% FBS | 39.7 nm (100%) | 0 | 0 |