Table 1.
Demographic and clinical characteristics of patients
| Characteristics | Nonshock sepsis (NSS) (n = 40) | Septic shock (n = 50) | |
|---|---|---|---|
| Septic shock, survivors (SSSs) (n = 40) | Septic shock, nonsurvival (n = 10) | ||
| Age (months), median (IQR) | 43 (14.3–67.5) | 24 (8.8–62.5) | 18 (8–54) |
| Age | |||
| <1 year, n (%) | 8 (20%) | 12 (30%) | 4 (40%) |
| 1–5 years, n (%) | 15 (37.5%) | 16 (40%) | 3 (30%) |
| >5 years, n (%) | 17 (42.5%) | 12 (30%) | 3 (30%) |
| Sex ratio (M:F) | 31:9 | 23:17 | 7:3 |
| Severe acute malnutrition, n (%)a | 3 (8) | 4 (10) | 0 (0) |
| BMI, median (IQR) | 14.8 (14–16) | 14.7 (13.4–16.3) | 15 (14–16.8) |
| Primary diagnosis | |||
| Pneumonia, n (%) | 15 (37.5) | 26 (65) | 5 (50) |
| CNS infections, n (%) | 8 (20) | 5 (12.5) | 2 (20) |
| Disseminated staphylococcal | 3 (30) | ||
| Sepsis, n (%) | 7 (17.5) | 7 (17.5) | |
| Enteric fever, n (%) | 3 (7.5) | 0 (0) | |
| Others | 7 (17.5) | 2 (5) | |
| Total number of dysfunctional organs at admission, mean (SD)b | 0.8 ± 0.3 | 3.1 ± 0.9 | 3.4 ± 0.8 |
| PeLOD score at admission, mean (SD)b | 2 ± 0.4 | 11.7 ± 5.1 | 15.3 ± 4.8 |
| Patients who received mechanical ventilation, n (%) | 19 (47.5%) | 20 (50%) | 10 (100%) |
| Duration of mechanical ventilation in days, mean (SD) | 6.3 ± 3.1 | 6.6 ± 2.9 | Till death |
| Patients who received inotropes, n (%)b | 0 (0%) | 40 (100%) | 10 (100%) |
| VIS (mean ± SD) on day 1b,c | 0 | 36.9 ± 19.4 | 63.0 ± 16.4 |
| Duration of inotropes in days, mean (SD) | – | 6.4 ± 2.5 | Till death |
| Hospital stay (days) (mean ± SD)b | 10.8 ± 2.6 | 15.2 ± 4.3 | 2.7 ± 1.1 |
aNational Center for Health Statistics (NCHS) median weight was used as reference; bSignificant difference between NSS patients and SSSs, p < 0.001; cSignificant difference between septic shock survivors and septic shock nonsurvivors, p < 0.001
IQR, interquartile range; PEM, protein energy malnutrition; BMI, body mass index; PeLOD score, pediatric logistic organ dysfunction score; VIS, vasoactive inotrope score; SD, standard deviation, NA, information not available