Figure 1.

Dissolution setup. The reservoir for the physiological fluid was controlled at 37 °C, as well as the flow-through cells. The peristaltic pump regulated the flow-rate of up to eight cells in parallel, with a programmable autosampler for fluid collection. The flow-through cell was equipped with 5 kDa membranes to hold back particles and only allow the flow of ions. The meniscus of the reservoir was elevated approx. 0.5 m above the cells such that the hydrostatic pressure balanced the pressure drop by the 5 kDa membrane.