Figure 1.

Timeline of exposure protocol for toxicological evaluation in BALB/c mice. The UP-CNTs and P-CNTs were characterized by SEM, and Raman spectroscopy; FITC functionalization was demonstrated by epi-fluorescence microscopy. Serum samples were obtained at 0, and 24 h, and later at 14, 29, and 60 days post inoculation of CNTs to determine the biochemical parameters. At the end of each time post inoculation, the animals were sacrificed, and the organs were dissected for histological observation.