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. 2020 Mar 12;12:1855–1862. doi: 10.2147/CMAR.S244406

Table 1.

Clinicopathological Characteristics of Study Subjects

Clinical Characteristics Total (n=391) SLNM Group (n=44) MLNM Group (n=347) p valuea
Age (9~77 years) 36.92±12.88 41.56±12.39 36.22±12.56 0.008b
Sex
 Male 124(31.7%) 17(38.6%) 107(30.8%) 0.295
 Female 267(68.3%) 27(61.4%) 240(69.2%)
Number of tumors
 Solitary 246(62.9%) 33(75%) 213(61.4%) 0.078
 Multifocality 145(37.1%) 11(25%) 134(38.6%)
Tumor size (0.1~9.7 cm) 2.14±1.31 2.08±1.48 2.23±1.29 0.461b
 >1cm 326(83.4%) 32(72.3%) 294(84.7%) 0.044
 ≤1cm 65(16.6%) 12(27.3%) 53(15.3%)
Capsular invasion
 Present 129(33%) 12(27.3%) 117(33.7%) 0.392
 Absent 262(67%) 32(72.3%) 230(66.3%)
Extrathyroidal extension
 Present 115(29.4%) 15(34.1%) 100(28.8%) 0.470
 Absent 276(70.6%) 29(65.9%) 247(71.2%)
Lymphocytic thyroiditis
 Present 146(37.3%) 15(34.1%) 131(37.8%) 0.636
 Absent 245(62.7%) 29(65.9%) 216(62.2%)
TSH level
 High 59(15.1%) 6(13.6%) 53(15.3%) 0.658
 Normal 322(82.4%) 36(81.8%) 286(82.4%)
 Low 10(2.5%) 2(4.6%) 8(2.3%)
Number of CLNM 2.37±2.27 1.64±2.27 3.84±4.64 0.000b
CLNM
 Present 327(83.6%) 25(56.8%) 302(87.0%) 0.000
 Absent 64(16.4%) 19(43.2%) 45(13.0%)

Notes: aPearson’s chi-squared test was adopted; bThe Student’s t‐test was adopted.

Abbreviations: SLNM, solitary lateral neck node metastasis; MLNM, multiple lateral neck node metastasis; TSH, thyroid stimulating hormone; CLNM, central lymph node metastasis.