Table 2.
Baseline Population Characteristics of Studies Examining Incidence and Prevalence of Atypical Hemolytic Uremic Syndrome
| Study Name | Study Period | Study Population | Incident Cases | Age at Onset (Range) | Male, n (%) | Acute Dialysis n (%) | Neurological Involvement n (%) | Serum Creatinine umol/L (Range) | Hemoglobin, g/dL (Range) | Platelets 10^9/L (%) | Anemia, n (%) | Diarrhea n (%) | Respiratory Infection n (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bayer 201924 | 2009–2016 | All ages | 15 | 35* (23–46)# | 4 (27) | 13 (86)√ | 5 (33) | 4.6* (1.7–7.9)#Ψ | 7.6* (6.2–9.9)# | 71* (40–80)# | 14 (95) | 3 (19) | – |
| Ardissino 201625 | 2003–2012 | ≤18 years | 12 | – | – | 4 (33.3) | – | – | – | – | – | 0 | – |
| Durkan 201628 | 1994–2001 | ≤15 years | 14 | 1.1* (0.28–14.7)Ω | 5 (36) | 10 (71) | 4 (29) | 219* (99–1253) | 3.8* (7.1–14.0) | 54* (9–147) | 14 (100) | 9 (64.3) | – |
| Jenssen 201426 | 1999–2008 | <16 years | 9 | – | – | – | – | – | – | – | – | 0 | – |
| Mallett 201429 | 2013 | >18 years | 3 | 36.66 | – | – | – | – | – | – | – | 0 | – |
| Wuhl 201427 | 2007–2011 | All ages | 288 | – | – | – | – | – | – | – | – | 0 | – |
| Fremeaux-Bacchi 201313 | 2000–2008 | <16 years | 89 | 1.5 (0–15) | 47 (52.8) | 48 (59) | 14 (16) | 257 (28–990) | 6.8 (3.0–12.0) | – | 79 (94) | 35 (39) | 7 (8) |
| ≥16 years | 125 | 31 (15–85) | 32 (25.6) | 93 (81) | 10 (8) | 640 (111–2408) | 7.2 (5.0–11.8) | – | 83 (89) | 19 (15) | 1 (1) | ||
| Zimmerhackl 200623 | 1974–2005 | <18 years | 167 | – | 94 (56.2) | – | – | – | – | – | – | 0 | – |
Notes: All values displayed as mean (range) or otherwise specified; *Median, #IQR, Ωconverted from months, √reported as acute kidney injury, Ψmg/dL.