Table 3.
Incidence and Prevalence of Atypical Hemolytic Uremic Syndrome
| Study | Country | Study Period | Age | Total aHUS Cases | Incidence per Million Annually (Range) | Prevalence per Million |
|---|---|---|---|---|---|---|
| Bayer 2019*24 | France | 2009–2016 | All ages | 15 | 1.9 | – |
| Ardissino 201625 | Italy | 2003–2012 | ≤18 years old | 12 | 0.75 | 9.4 |
| Durkan 201628 | Australia | 1994–2001 | ≤15 years old | 14 | 0.44 | – |
| Jenssen 201426 | Norway | 1999–2008 | <16 years old | 9 | <1 (0–3) | – |
| Mallett 201429 | Australia/New Zealand | 2013 | >18 years old | 3 | – | 2.4 |
| Wuhl 201427 | Austria, Denmark, Spain, Finland, France, Greece, Netherlands, Norway, Romania, Sweden, Scotland | 2007–2011 | All ages | 815 | 0.39 | 4.96 |
| 2007-2011 | <20 years old | 81 | 0.26 | 2.21 | ||
| 2007–2011 | >20 years old | 734 | 0.42 | 5.75 | ||
| Fremeaux-Bacchi 201313 | France | 2000–2008 | All ages | 214 | 0.23 | – |
| Zimmerhackl 200623 | Austria, Germany, Czechia, Hungary, Switzerland, United Kingdom, Italy, Turkey, Netherlands, Israel, Sweden, France | 1974–2005 | <18 years old | 167 | – | 3.3 |
Note: *One pediatric case in the study.