. Author manuscript; available in PMC: 2020 Oct 16.

Published in final edited form as: J Am Chem Soc. 2019 Oct 2;141(41):16260–16265. doi: 10.1021/jacs.9b09344

Table 2.

Substrate Scope^a,b

graphic file with name nihms-1570671-t0003.jpg

The reaction was run on a 0.1 mmol scale.

All yields are isolated yields; ee was determined by chiral HPLC; selectivity (s) = ln[(1 − C)(1 − ee_SM)]/ln[(1 − C)(1 + ee_SM)], calculated conversion (C) = ee_SM/(ee_SM + ee_PD).

Reaction was carried out with [Rh(CH₂=CH₂)₂Cl]₂ (10 mol%), (R)-DTBM-segphos (20 mol%), AgSbF₆ (20 mol%), THF (1 mL) at 40 °C.