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. 2019 Nov 28;221(7):1135–1145. doi: 10.1093/infdis/jiz563

Table 1.

Demographic and Baseline Clinical Characteristics of Participantsa

Characteristic Participants, No. (%)b
Male sex 60 (100)
Age, median (IQR), y 34 (28–41)
Interval median (IQR), d
 From confirmed HIV-positive test to ART initiation 29 (14–47)
 From estimated date of seroconversion to ART initiation 49 (32–93)
 From ART initiation to first VL <50 copies/mLc 133 (90–230)
Baseline values, median (IQR)
 CD4 T-cell count, cells/μLd 530 (409–663)
 CD8 T-cell count, cells/μLd 1037 (837–1318)
 CD4/CD8 ratiod 0.5 (0.4–0.8)
 VL, log10 copies HIV RNA/mL 5.4 (4.5–6.4)
Method for diagnosing primary HIV infection
 Antigen positive (p24 or PCR) but antibody negative 25 (42)
 Rising antibody titer 1 (2)
 Negative test result within 6 mo of positive result 28 (47)
 Recent incidence testing algorithm 6 (10)
Mode of acquisition
 MSM 54 (90)
 MSW 1 (2)
 Unknown/unrecorded 5 (8)
Initial ART regimen
 Unknown/unrecorded 3 (5)
 Backbone
  Tenofovir containing 52 (87)
  Abacavir containing 5 (8)
 Additional agent(s)
  Protease inhibitor 33 (55)
  NNRTI 11 (18)
  Integrase inhibitor 12 (20)
  Protease inhibitor plus integrase inhibitor 1 (2)

Abbreviations: ART, antiretroviral therapy; HIV, human immunodeficiency virus; MSM, men who have sex with men; MSW, men who have sex with women, NNRTI, nonnucleoside reverse-transcriptase inhibitor; PCR, polymerase chain reaction; VL, viral load.

aDemographic and baseline clinical characteristics of included participants from the HEATHER cohort.

bData represent no. (%) of participants unless otherwise identified as median (IQR) values.

cFifty-nine of 60 individuals were virologically suppressed to <50 copies/mL before 1-year study visit; the remaining individual achieved virological suppression shortly thereafter, at the next VL measurement (Supplementary Figure 1)

dData available for 59 of 60 individuals.