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. 2019 Nov 28;221(7):1135–1145. doi: 10.1093/infdis/jiz563

Table 2.

Predictors of Reservoir Size at 1 Yeara

Predictors Coefficient
Model A Model B
Baseline log10 total HIV DNA 0.29 0.27
Time from ART start to VL suppression (d) 0.00031

Abbreviations: ART, antiretroviral therapy; HIV, human immunodeficiency virus; VL, viral load.

aLeast absolute shrinkage and selection operator (LASSO) output for predictors of reservoir size (total HIV DNA level at 1 year). Model A includes all baseline clinical and immunological variables, including baseline total HIV DNA levels (50 predictors; n = 60; deviance explained, 0.49). Model B includes all immunological measures at 1 year along with baseline total HIV DNA level (44 predictors; n = 60; deviance explained, 0.42). Variables that do not significantly contribute to the model have a coefficient of 0; only those with a nonzero coefficient are shown. Missing values were imputed. Coefficients represent the change in log10 total HIV DNA per unit predictor variable.