Table 2.
Predictors | Coefficient | |
---|---|---|
Model A | Model B | |
Baseline log10 total HIV DNA | 0.29 | 0.27 |
Time from ART start to VL suppression (d) | 0.00031 | … |
Abbreviations: ART, antiretroviral therapy; HIV, human immunodeficiency virus; VL, viral load.
aLeast absolute shrinkage and selection operator (LASSO) output for predictors of reservoir size (total HIV DNA level at 1 year). Model A includes all baseline clinical and immunological variables, including baseline total HIV DNA levels (50 predictors; n = 60; deviance explained, 0.49). Model B includes all immunological measures at 1 year along with baseline total HIV DNA level (44 predictors; n = 60; deviance explained, 0.42). Variables that do not significantly contribute to the model have a coefficient of 0; only those with a nonzero coefficient are shown. Missing values were imputed. Coefficients represent the change in log10 total HIV DNA per unit predictor variable.