Table 4:
Pain Intensity, SURF Study
| 10-kHz High-Frequency SCS | Comparator SCSa | Difference | |
|---|---|---|---|
| Back-Pain Intensity | |||
| VAS, baseline, mm | 75.8 ± 13.1 | 77.5 ± 9.9 | −1.7 |
| VAS, 6 months, mm | 17.8 ± 14.1 | 27.8 ± 23.2 | −10 |
| VAS change, points (%) | 58.0 (77) | 49.7 (64) | 8.30 |
| Responder rate, %b | 92 (95% CI 79.2–97.3) | 82 (95% CI 66.4–91.2) | 10.0 |
| Remitter rate, %c | 84 (95% CI 72.3–95.7) | 47 (95% CI 30.2–63.8) | 37.0 |
| Leg-Pain Intensity | |||
| VAS, baseline | 55.1 ± 27.2 | 61.5 ± 24.1 | −6.4 |
| VAS, 6 months | 13.3 ± 14.1 | 22.3 ± 24.4 | −9.0 |
| VAS change, points (%) | 41.8 (76) | 39.2 (64) | 2.6 |
| Responder rate, %b | NR | NR | — |
| Remitter rate, %c | NR | NR | — |
Abbreviations: CI, confidence interval; NR, not reported; SCS, spinal cord stimulation; VAS, visual analog scale.
a
Comparator SCS protocols included low-frequency, burst, and 1.2–1.5 kHz moderate-frequency.
b
Pain score >50% reduction over baseline.
c
Pain score ≤ 25 mm.
Source: Bolash et al, 2019.28