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. 2019 Dec 24;36(6):1731–1739. doi: 10.1093/bioinformatics/btz845

Table 1.

Bioinformatic tool scorecard

IMGT/ HighV-QUEST IgBLAST MiXCR
Computational experience +++ + +
Reference germline options + +++ ++
Speed + ++ +++
Accuracy ++ +++ +
Gene naming granularity +++ (allele) +++ (allele) + (gene)
Reproducibility with other tools ++ +++ +
Number of unique clones ++ ++ +a
a

MiXCR performs clonotyping which results in lower number of unique clones.