Table 1.
IMGT/ HighV-QUEST | IgBLAST | MiXCR | |
---|---|---|---|
Computational experience | +++ | + | + |
Reference germline options | + | +++ | ++ |
Speed | + | ++ | +++ |
Accuracy | ++ | +++ | + |
Gene naming granularity | +++ (allele) | +++ (allele) | + (gene) |
Reproducibility with other tools | ++ | +++ | + |
Number of unique clones | ++ | ++ | +a |
MiXCR performs clonotyping which results in lower number of unique clones.