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Estimation of arbitrary structured background from images of various PSFs. Shown are the probability density function of the PSF (i.e. the noise-free, theoretical PSF), the PSF with background, the true underlying background in the PSF image, the prediction of BGnet, and the background-corrected PSFs, using either the true or the predicted background. Scale bar: 500 nm (open aperture PSF), 1 µm (other PSFs).
