Table 4. Performance results from all optical imaging modalities for the salivary tumor cohort, separated by salivary gland group (average ± SEM). The best performing modality for each groups’ evaluation metrics is bolded.

Group	Imaging	AUC	Accuracy	Sensitivity	Specificity
Parotid (N = 3)	HSI	0.92 ± 0.04	88 ± 4%	90 ± 4%	79 ± 7%
	Autofluorescence	0.60 ± 0.30	87 ± 2%	99 ± 1%	26 ± 26%
	2-NBDG Dye	0.77 ± 0.12	87 ± 2%	97 ± 3%	31 ± 31%
	Proflavin Dye	0.64 ± 0.32	89 ± 2%	96 ± 2%	54 ± 27%
	Gaussian-RGB	0.66 ± 0.15	81 ± 5%	97 ± 2%	38 ± 24%
	Human-Eye	0.72 ± 0.02	78 ± 15%	95 ± 5%	35 ± 20%
Other Salivary (N = 3)	HSI	0.59 ± 0.14	76 ± 12%	55 ± 29%	85 ± 15%
	Autofluorescence	0.80 ± 0.14	84 ± 10%	77 ± 13%	85 ± 6%
	2-NBDG Dye	0.52 ± 0.08	76 ± 11%	49 ± 28%	84 ± 16%
	Proflavin Dye	0.62 ± 0.10	77 ± 11%	60 ± 30%	78 ± 22%
	Gaussian-RGB	0.45 ± 0.03	70 ± 10%	62 ± 31%	57 ± 43%
	Human-Eye	0.78 ± 0.15	84 ± 9%	76 ± 12%	87 ± 6%