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. 2016 Feb 15;59(14):6595–6628. doi: 10.1021/acs.jmedchem.5b01461

Table 6. Inhibitory Activity of Halomethyl Ketonesa.

4.6.

compd R X IC50 (μM)
61 see above structure see above structure 10
62 Bn Cbz-Leu 15
63 Bn Cbz-Phe 20
64 Me Boc-Leu 40
65 H Boc-γ-Glu(OtBu)-Ala 40
66 H γ-Glu-Ala 50
67 Bn CH3(CH2)8CO-Leu 50
68 Bn CH3(CH2)7CO-Leu >50
a

IC50, half-maximal inhibitory concentration; Bn, benzyl; Me, methyl.