Table 1. Inhibitory Activities of Lipopeptides on MERS-CoV S Protein-Mediated Cell–Cell Fusiona.
The number of 293T/MERS/EGFP cells fused or unfused with Huh-7 cells were countered, and the percentage of inhibition was calculated as described in the experimental section. Data were derived from the results of three independent experiments and are expressed as the mean ± standard deviation.
These peptides have an acetyl group at the N-terminus and carboxyamide at the C-terminus. The letters a-g indicate the positions of the corresponding residues in a helical wheel presentation. βA, β-alanine.
Cytotoxicity to Huh-7 cells.