. 2018 Sep 7;61(19):8734–8745. doi: 10.1021/acs.jmedchem.8b00890

Table 3. Pharmacokinetic Parameters of IIQ in Rats Following a Single Dose iv Administration Calculated by Noncompartmental Analysis by Using DAS, Version 3.2.8^a.

compd	AUC (0–t) ((μg/mL)·h)	MRT (0–t) (h)	t_1/2 (h)	CL ((mL/h)/kg)	C_max (μg/mL)	V_d (mL/kg)
IIQ	234.7 ± 7.8	4.1 ± 0.1	6.6 ± 0.2	20.7 ± 0.6	97.6 ± 8.4	197.8 ± 9.3

MRT, mean residence time; CL, clearance; V_d, volume of distribution.

Table 3. Pharmacokinetic Parameters of IIQ in Rats Following a Single Dose iv Administration Calculated by Noncompartmental Analysis by Using DAS, Version 3.2.8a.