Table 2.

Cox proportional hazards analyses

Model	Dependent variable	Predictor	HR (95% CI)	p-value
Multivariate	PFS	Broadband power	2.56 (1.15–5.70)	0.022*
		Age	0.93 (0.91–0.97)	0.032*
		IDH-mut/codel	Reference	–
		IDH-mut/non-codel	13.18 (1.61–17.02)	0.016*
		IDH-wt	52.44 (5.28–521.19)	0.001*
Post-hoc univariate	OS	Broadband power	1.94 (1.04–3.62)	0.038*
Post-hoc multivariate	OS	Broadband power	3.74 (1.23–11.36)	0.020*
		Age	1.05 (0.97–1.23)	0.30
		IDH-mut/codel	Reference	–
		IDH-mut/non-codel	5641.31 (0–1.16 × 1042)a	0.85
		IDH-wt	5.19 × 1012 (0–4.19 × 1010)a	0.80
		KPS	1.06 (0.97–1.15)	0.20
		Epilepsy	125.60 (2.20–7159.94)	0.019*
		Grade II	Reference	–
		Grade III/IV	0.010 (0–1.42 × 1036)	0.92

95% CI 95% confidence interval, HR hazard ratio, IDH isocitrate dehydrogenase, IDH-mut/codel IDH-mutant, 1p19q codeleted, IDH-mut/non-codel IDH-mutant, 1p19q non-codeleted, IDH-wt IDH-wildtype, KPS Karnofsky performance score

*p < 0.05

^aNo people died in the reference group