Table 1.
Demographic characteristics of subjects.
| AA (n = 5) |
AC (n = 31) |
AA + AC (n = 36) |
CC homozygotes (n = 43) |
p-value (AA + AC vs. CC)a | |
|---|---|---|---|---|---|
| Age, mean ± s.d. (range) | 43 ± 14 (21–56) | 42 ± 12 (21–71) | 42 ± 12 (21–71) | 38 ± 14 (20–70) | 0.20 |
| Gender (M, F) | 2, 3 | 20, 11 | 22, 14 | 27, 16 | (χ2 = 0.022)b 0.83 |
| Ethnicity (White, Hispanic, Asian, Black, American Indian, South Asian, Egyptian, Mixed), n | 1, 3, 1, 0, 0, 0, 0, 0 | 24, 0, 1, 2, 0, 2, 2, 0 | 25, 3, 2, 2, 0, 2, 0, 2 | 30, 1, 6, 2, 1, 2, 1, 0 | (χ2 = 6.888)b 0.44 |
| Body mass index (kg/m2), mean ± s.d. (range) | 27 ± 5 (23–36) | 25 ± 4 (19–34) | 25 ± 4 (19–36) | 25 ± 3 (19–31) | 0.38 |
| Cigarette smokers, n | 3 | 10 | 13 | 8 | (χ2 = 2.632)b 0.11 |
| Current alcohol use/week, mean ± s.d. (range) | 2.90 ± 4.22 (0–10) | 0.98 ± 1.95 (0–8) | 1.25 ± 2.39 (0–10) | 1.28 ± 2.39 (0–12) | 0.95 |
| HRRT vs. PET/CT, n | 5, 0 | 19, 12 | 24, 12 | 22, 21 | (χ2 = 2.415)b 0.12 |
| Mass injected (µg), mean ± s.d. | 7.83 ± 1.42 | 9.00 ± 1.36 | 8.84 ± 1.41 | 9.07 ± 0.96 | 0.40 |
| Corrected activity (mCi), mean ± s.d. | 883 ± 205 | 1097 ± 321 | 1067 ± 314 | 1079 ± 312 | 0.86 |
| Specific activity (mCi/µmol), mean ± s.d. | 2.21 ± 0.13 | 2.14 ± 0.31 | 2.15 ± 0.29 | 2.19 ± 0.31 | 0.56 |
There were no significant differences between AA and AC groups in any of the parameters presented here
aGroup comparisons were done between CC (n = 43) vs. AA + AC (n = 36)
bComparisons of proportions were carried out using Chi-Square tests between CC (n = 43) vs. AA + AC (n = 36)