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. 2020 Mar 16;10:4800. doi: 10.1038/s41598-020-61710-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The immune landscape of 17 immune cell types. (A) Forest plot visualizing hazard ratios (HRs) with 95% CI and P-values for 17 immune cell types. Kaplan-Meier survival curves by high and low tumor infiltrating levels for (B) cytokine receptors, (C) interleukins and (D) TGFb family member receptor. (E) The spearman’s correlation between the tumor infiltrating levels of 17 immune cell types and tumor purity, ESTIMATE score, stromal score, immune score and CYT. Statistical significance at the level of null ≥0.05, * < 0.05, ** < 0.01 and *** < 0.001. (F) The Spearman’s correlation between tumor purity, ESTIMATE score, stromal score, immune score and CYT.